Have you tried simply creating a new controller profile? Delete (or temporarily remove) the current T500 profile you have, then launch rf2 and click on [detect].
Did you check that vehicle set is not selected? If it is, then the game will try to override your profiler settings.
May i ask, why the 270 degree rotation? Even F1 uses more than that. From my opinion, if you want to simulate the cars properly, you need to use at least 900 in the profiler and enable vehicle set in game - rF2 does the rest and the rotation then matches perfectly. Of course, you may well have a valid reason for the 270 (like one of my league mates who is disabled).
John, Guy, I tried your suggestions;
-Creating a new controller profile made no difference. Deleted the customized T500RS I had, did auto-detect in game, no good.
-I have always left the default settings as "vehicle set", never been a problem.
-I use 270 degrees because it seems to work best with all of my other SIMs (rF1 especially, pCARS, AC, etc.), including rF2. I will try and use 900 degree again.
-Lastly, I deleted my "PLR" file, set everything back the way it usually is (270d), went back in-game and did the auto-detect for the wheel. This SOLVED IT!
At least temporarily the wheel is behaving as expected. I will continue to drive/test the v382 build, if it happens again I suspect there is some sort of corruption occurring to the "*.plr" file.
I really appreciate the feedback, this has been an odd issue, if widespread it may help others resolve it. Thank you!