First time for me. I got a hard crash while driving at Indy with the DW12. I entered the track just after going out of the pits, some car was coming from behind, I heard a "Inside... inside..." from the spotter, and then I had a CTD with the dialog box "rFactor2 application stopped working" or something like that. Had my delta best x64 plugin enabled (and working afaict). After this, I restarted rf2, did another two-three sessions without any problems (with the plugin).
Got another CTD while driving the DW12 at Lime Rock Park. This is definitely not normal. Both times (see above) I was driving the DW12 and both times I had my delta best x64 plugin running. To exclude the plugin as a source of problems, I will disable it now, but my hunch is that something's wrong here.
Did a practice run with same track (Indy oval) and car, 25 AI drivers, 64bit, no plugins. I let the session run for an hour, drove a few laps sometimes, no problems in my case.
I run some more laps without plugin and I never had a CTD so far. Most reasonable option is that the plugin is causing it, but I wouldn't know why.